Today’s drug delivery devices are elaborate. It does not matter if the device is a peripheral venous catheter, a syringe, a pen injector, an autoinjector or a wearable injector (pump), the most common element in each device – and arguably the most important – is the needle. In fact, although it begins as a blank stainless-steel rod, by the time a patient uses the injection device, the needle has undergone a dramatic transformation.