NETZSCH-Gerätebau GmbH – Thermal Analysis – Perfect Tools for Compatibility Screening

Finished pharmaceutical products usually consist of many ingredients, namely the API and several excipients. The excipients assume different functions, e.g., as processing aids, as stabilizers or as release-controlling agents. In any case, the individual components should not negatively influence each other, so that efficacy and stability of the API are always maintained. This needs already to be worked out during formulation development as described in ICH Q8(R2).